Descriptions:Galectin-4 (Gal-4) is a lectin family member and is one of the tandem repeat-type galectins containing two carbohydrate recognition domains (CRD) connected by a linker region in a single peptide chain. The CRD is responsible for β-galactoside binding, and several binding partners for galectin-4 have been identified, including human blood group antigens, glycoproteins, mucin like membrane MUC1, glycosphingolipids, and sulfated cholesterol. Galectin-4 is constitutively presented in the intestine and stomach, uterine epithelial cells, blood vessel walls, hippocampal and cortical neurons. It serves important functions in numerous biological activities including lipid raft stabilization, protein apical trafficking, cell adhesion, wound healing, intestinal inflammation, and host defense.
Tags:Galectin-4
Descriptions:IL-5 is a 45-60 kDa homodimer cytokine that functions principally in the eosinophil arm of the Th2 response. It is a member of the helical bundle family of cytokines, along with IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF).
Tags:IL-5
Descriptions:Fibroblast Growth Factors-4 (FGF-4) is a 22 kDa member of the fibroblast Growth Factors with 206 amino acid residues. FGF-4 can regulate embryonic development, cell proliferation, and cell differentiation. FGF-4 is an important role development during embryogenesis.
Tags:FGF-4
Descriptions:R-spondin 1 (RSPO1, Roof plate-specific Spondin 1) is a cysteine-rich secreted glycoprotein that belongs to the R-Spondin family. Structurally, R-spondin 1 harbors an N-terminal signal peptide, two cysteine-rich furin-like (FU1-FU2) domains, a thrombospondin (TSP) domain, and a basic amino acid-rich (BR) C-terminal domain. R-spondin 1 acts as a ligand for the leucine-rich repeat-containing G-protein coupled receptor (LGR) family (LGR4/5/6), subsequent clearing negative regulators ZNRF3/RNF43 from the membrane, leading to the availability of Wnt receptor and activating Wnt/β-catenin signaling. The signal cascade is essential for regulating stem cell proliferation, embryonic development, and tissue homeostasis.
Applications:His-SUMO tag
Tags:RSPO1/R-spondin 1
Descriptions:Glutaminase (GLS)
Tags:Glutaminase (GLS)
Descriptions:Acetyl CoA Carboxylase (ACC)
Descriptions:Fibroblast Growth Factors-5 (FGF-5) is a 29.6 kDa member of the fibroblast Growth Factors with 268 amino acid residues. FGF-5 have an important role in the regulation of cell proliferation and cell differentiation. In physiological function, FGF5 is a crucial regulator of hair growth in humans.
Applications:His tag
Tags:FGF-5
Descriptions:Formaldehyde Dehydrogenase (FDH)
Descriptions:Ethanol
Tags:Ethanol