Descriptions:Bone Morphogenetic Protein-9 (BMP-9), known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-8B can bind with the TGF-β receptor and trigger SMAD protein signal transduction. BMP-9 is the most effective for the differentiation of osteoblasts in vivo, and the general BMP blocker does not affect it.
Applications:His tag
Tags:BMP-9
Descriptions:NADP phosphatase (NADPase) is mainly present in plant tissues and is the only enzyme in organisms that catalyzes the degradation of NADP+ to NAD+. Together with NADK, it regulates the balance between NAD and NADP.
Descriptions:Interleukin 24 (IL-24) predicts a molecular mass of 18.2 kDa, is a cytokine belonging to the IL-10 family of cytokines that signals through IL-20R1 /IL-20R2 and IL-22R1 /IL-20R2. Its normal physiological role relates to wound healing, protection against diseases caused by bacteria.
Applications:His tag
Tags:IL-24
Descriptions:Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is secreted by a number of different cell types (including activated T cells,Bcells,macrophages,mast cells,endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation.
Applications:His tag
Tags:M-CSF
Descriptions:Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immune responses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13.
Tags:IL-4
Descriptions:Human DKK-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of DKK-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Human DKK-1 inhibition is critical for bone formation and homeostasis. In addition, Human DKK-1 can act as either a tumor suppressor or promoter of metastasis.
Tags:DKK-1
Descriptions:Cholera toxin (CT) is an AB5 enterotoxin produced by Vibrio cholerae and is responsible for the disease manifestations. Several publications indicate that the toxin binds to glycoprotein and that the B-chain binds to GM1 ganglioside pentasaccharide on the cell surface.
Tags:Toxin B
Descriptions:Interleukin 20 (IL-20) predicts a molecular mass of 17.6 kDa. The IL-20 subfamily of cytokines is comprised of IL-19, IL-20, IL-22, IL-24, and IL-26. It regulates of differentiation of keratinocytes during inflammation, the expansion of multipotential hematopoietic progenitor cells.
Tags:IL-20
Descriptions:Galectin-3 (Gal-3) is one of the lectin family members, which is the only chimera‑type galectin, containing one carbohydrate recognition domain (CRD) connected to a long, flexible N‑terminal domain. The C‑terminal CRD is responsible for β-galactoside binding, and the N‑terminal domain is essential for its multimerization, and interaction with other intracellular proteins. Galectin-3 is predominantly presented in the cytoplasm and expressed on the cell surface, and then often secreted into biological fluids, such as serum and urine. Numerous studies have indicated that galectin-3 plays a crucial role in cell proliferation, apoptosis, gene expression, immune surveillance, inflammation, fibrosis, and host defense.
Tags:Galectin-3
Descriptions:Fibroblast Growth Factors-3 (FGF-3) also known as INT-2 proto-oncogene, is a 26.9 kDa member of the fibroblast Growth Factors with 239 amino acid residues. FGF-3 regulates embryonic development, cell proliferation and cell differentiation.
Tags:FGF-3