Descriptions:C-X-C motif chemokine 5 (CXCL5) also named epithelial-derived neutrophil-activating peptide 78 (ENA-78), which is a chemokine of the intercrine alpha family. CXCL5 is a 8kDa protein containing 70 amino acid residues. CXCL5 is stimulated by the IL-1 or TNFα during inflammation which produced by the eosinophils and CXCL5 is inhibited by the IFNγ. CXCL5 promotes the formation of blood vessels and angiogenesis by binding the cell receptor CXCR2.
Tags:CXCL5
Descriptions:CA is a common organic acid in organism and an important food flavor substance. In addition, CA is the product of the first step of the tricarboxylic acid cycle.
Tags:Citric Acid (CA)
Descriptions:Human DKK-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of DKK-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Human DKK-1 inhibition is critical for bone formation and homeostasis. In addition, Human DKK-1 can act as either a tumor suppressor or promoter of metastasis.
Tags:DKK-1
Descriptions:Hepatic Lipase (HL)
Tags:Hepatic Lipase (HL)
Descriptions:Galectin-3 (Gal-3) is one of the lectin family members, which is the only chimera‑type galectin, containing one carbohydrate recognition domain (CRD) connected to a long, flexible N‑terminal domain. The C‑terminal CRD is responsible for β-galactoside binding, and the N‑terminal domain is essential for its multimerization, and interaction with other intracellular proteins. Galectin-3 is predominantly presented in the cytoplasm and expressed on the cell surface, and then often secreted into biological fluids, such as serum and urine. Numerous studies have indicated that galectin-3 plays a crucial role in cell proliferation, apoptosis, gene expression, immune surveillance, inflammation, fibrosis, and host defense.
Tags:Galectin-3
Descriptions:NADP phosphatase (NADPase) is mainly present in plant tissues and is the only enzyme in organisms that catalyzes the degradation of NADP+ to NAD+. Together with NADK, it regulates the balance between NAD and NADP.
Descriptions:Fibroblast Growth Factors-3 (FGF-3) also known as INT-2 proto-oncogene, is a 26.9 kDa member of the fibroblast Growth Factors with 239 amino acid residues. FGF-3 regulates embryonic development, cell proliferation and cell differentiation.
Tags:FGF-3
Descriptions:Macrophage Colony Stimulating Factor (M-CSF) is a 18.54 kDa member of hematopoietic Growth Factors with 159 amino acid residues. M-CSF produced by osteoblasts and osteoblast precursors. M-CSF stimulates the growth and differentiation of the monocyte lineage, and promotes the survival, proliferation, and functions of mature monocytes/macrophages.
Tags:M-CSF
Descriptions:Glutamine synthase (GS, EC 6.3.1.2) is mainly present in plants and is one of the key enzymes for ammonia assimilation in organisms.