Descriptions:Ciliary Neurotrophic Factor (CNTF) is the member of IL-6 cytokine family and mainly expressed in the nervous system. Mouse CNTF shares 84% sequence homology with human CNTF. CNTF is 22.9 kDa neurotrophic factor containing 110 residues, which shows multiple effects in vertebrate retinogenesis. Besides, CNTF acts as a promoter that not only accelerates adult neurogenesis but also increases the survival of neuron after injury.
Tags:CNTF
Descriptions:Basic fibroblast Growth Factors (FGF-2, bFGF), a pleiotropic cytokine, plays multiple roles in different cells and tissues. FGF-2 can stimulate smooth muscle cell growth, wound healing, and tissue repair. In addition, FGF-2 has been shown to regulate the generation of neurons and astrocytes from progenitor cells. FGF-2 are also involved in a variety of biological processes, including embryonic development, morphogenesis, tissue repair, tumor growth, and invasion. As a multifunctional cytokine, FGF-2 is first isolated from the pituitary. Later, it was identified from various cell types including cardiac myocytes, cardiac fibroblasts, endothelial cells, and smooth muscle cells.
Tags:FGF-2
Descriptions:Vascular Endothelial Growth Factors 165(VEGF165) is a potent growth and angiogenic cytokine which belongs to the VEGF family, includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. Human VEGF165 is an abundant glycosylated cytokine composed of two identical 165 amino acid chains. Human VEGF165 plays an important role in embryonic vasculogenesis, angiogenesis and neurogenesis.
Tags:VEGF165
Descriptions:C-C Motif Chemokine Ligand 2 (CCL2) is a 13.88 kDa cytokine with 125 amino acid residues and is also known as monocyte chemoattractant protein 1 (MCP1). CCL2 is mainly secreted from monocytes, macrophages, and dendritic cells. It regulates many biological functions, such as recruitments of monocytes, memory T cells, eosinophils, and dendritic cells, extravasation of helper T cells, response to TNFα and IFNγ, and angiogenesis. In addition, upon binding with CCR4, it initiates leukocyte migration response to inflammation.
Tags:CCL2
Descriptions:Glial cell line-derived neurotrophic factor (GDNF) is the neurotrophic factor, belonging to the GDNF family of ligands (GFL) and identifying as a therapeutic candidate in Parkinson's disease. GDNF is a 23.7 kDa protein containing 211 residues that plays a critical role in promoting the survival and differentiation of midbrain dopamine neurons. Besides, GDNF is revealed to facilitate the development of peripheral tissues such as kidney, pancreas and lung. Additionally, as a member of GFL, GDNF also takes part in the progression of tumor.
Tags:GDNF
Descriptions:α-Galactosidase (α-GAL, EC 3.2.1.22) is widely present in animals, plants, microorganisms, and cultured cells, and can specifically catalyze α-The hydrolysis of galactoside bonds mainly participates in the degradation of galactosides such as raffinose, stachyose, melibiose, and galactomannan. α-GAL is crucial for the germination of plant seeds. In the early stages of seed germination, the D-galactose catalyzed by α-GAL is rapidly converted and consumed through glycolysis, providing the initial energy source for seed germination.
Descriptions:Ferric reductase (FCR) catalyzes the reduction of Fe 3+ to Fe 2+ , in high valent iron chelates, which plays an important role in the absorption of iron in some species. Fe 2+ will react with ferrozine to develop color, and there is a characteristic absorption value at 562 nm.
Descriptions:The sulfhydryl group in organism mainly includes non-protein sulfhydryl group and protein sulfhydryl group. Sulfhydryl compounds have important detoxification function in vivo. It has very important physiological significance to the self-regulation of organism.
Descriptions:Mouse IL-18 Protein, His tag (Animal-Free), expressed in E. coli
Tags:IL-18
Descriptions:SuperKine™ Trypsin-EDTA Solution,0.25% (Without Phenol Red), and the pH value is 7.2-7.4. After filtration and sterilization, the digestive solution can be directly used for the digestion of cultured cells or some tissues.
Applications:Cell culture