Descriptions：Interleukin-4 (IL-4) is a key cytokine produced by activated T cells, mast cells, basophils, neutrophils and eosinophils. IL-4 is critical for the development of Th2-mediated responses, which is related to allergy and asthma. It can also regulate B cell responses, including survival, cell proliferation and gene expression. IL-4 also plays fundamental role for B-cell stimulation, including induction of the IgE isotype switch.
Tags：IL-4
Descriptions：In the presence of ATP, magnesium ions and oxygen, Luciferase (also known as Firefly Luciferase) can catalyze firefly luciferin to Oxyluciferin, which generate light signals during the oxidation of luciferin. In a certain range, the fluorescence intensity is proportional to the concentration of ATP.
Tags：ATP
Descriptions：Vascular Endothelial Growth Factors 165 (VEGF165) is a potent growth and angiogenic cytokine which belongs to the VEGF family, includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF165 is an abundant glycosylated cytokine composed of two identical 165 amino acid chains. VEGF165 plays an important role in embryonic vasculogenesis, angiogenesis and neurogenesis.
Tags：VEGF165
Descriptions：Human IL-21 Protein, His tag (Animal-Free), expressed in E. coli
Tags：IL-21
Descriptions：Receptor activator of NF-κB (RANK) ligand (RANKL) is type II transmembrane protein with an extracellular domain at the carboxy-terminus of TNF cytokine superfamily. RANKL is a 19.8 kDa protein containing 317 residues and high express in T cells and T cell rich organs, such as thymus and lymph nodes. RANKL-RANK (RANKL receptor) plays an important role in bone metabolism, dysregulation, and immune system.
Tags：RANKL
Descriptions：SuperKine™ Trypsin-EDTA Solution,0.25% (Without Phenol Red), and the pH value is 7.2-7.4. After filtration and sterilization, the digestive solution can be directly used for the digestion of cultured cells or some tissues.
Applications：Cell culture
Descriptions：Propidium Iodide (PI), molecular formula C27H34I2N4, molecular weight 668.4, CAS number 25535-16-4, is a nucleic acid fluorescent dye, can be used to stain mammals, bacteria, yeast. It cannot penetrate living cell membranes, but can penetrate the cell membranes of dead cells and late apoptotic cells to stain the nucleus.
Tags：PI
Descriptions：Interleukin 13 (IL-13) with a molecular mass of 10 kDa cytokine, it secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, eosinophils and nuocytes. It is homologous to IL-4 and shares many of its biologic activities on mononuclear phagocytic cells, endothelial cells, epithelial cells, and B cells.
Tags：IL-13
Descriptions：Interferon-Beta 1a (IFN-beta 1a) is a leukocyte interferon, which is a variant of Interferon-beta. IFN-beta 1a is a 19 kDa protein containing 166 amino acid residues. It could bind the interferon receptors that activates the signal transduction of immune responses through the Jak/STAT pathway in leukocytes and lymphoblastoid cells.
Tags：IFN-β1a
Descriptions：Bone morphogenetic protein -4 (BMP-4) is one of nine structurally related BMP's, belonging to transforming growth factor-β (TGF-β) superfamily, which secretes proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 treatment promoted the proliferation of HCC cells and induced autophagy. Mechanism study shows that autophagy induced by BMP-4 is mediated by activating JNK1/Bcl2 pathway. JNK1 inhibitor and JNK1 knockout can weaken BMP-4-induced autophagy and eliminate BMP-4-promoted HCC cell growth. BMP-4 promotes the proliferation of HCC through autophagy activation of JNK1/Bcl-2 signaling.
Tags：BMP-4
