Descriptions：FGF16 is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes, that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart.
Tags：FGF16
Descriptions：C-X-C motif chemokine 9 (CXCL9) also named monokine induced by gamma interferon (MIG), which is a chemokine of the intercrine alpha family. CXCL9 is a 11.4kDa protein containing 103 amino acid residues. CXCL9 controls the immune cells by binding the CXCR3 which is including the cell migration and activation. During inflammation, CXCL9 is a chemotaxis for lymphocyte and macrophages. CXCL9 is participated in the process of tumor proliferation and metastasis.
Tags：CXCL9
Descriptions：Betaine
Tags：Betaine
Descriptions：Fibroblast Growth Factors-20 (FGF-20) is a 23.5 kDa member of the fibroblast Growth Factors with 211 amino acid residues. FGF-20 is mainly expressed from microglial cells. FGF-20 can regulate central nervous development and function, regulate the survival of dopaminergic neurons via FGF/FGFR-dependent signaling pathway.
Tags：FGF-20
Descriptions：Interleukin 17B (IL-17B) predicts a molecular mass of 20.4 kDa, is expressed in several peripheral tissues and immune tissues. In contrast to the high level of IL-6 secretion stimulated by IL-17A, IL-17B failed to induce IL-6 secretion in fibroblasts; however, it significantly enhanced the TNF-α-induced production of G-CSF and IL-6 in the fibroblasts.
Tags：IL-17B
Descriptions：Fibroblast Growth Factors-6 (FGF-6) is a 22.9 kDa member of the fibroblast Growth Factors with 208 amino acid residues. FGF-6 is an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. In physiological function, FGF6 is required for normal muscle regeneration.
Applications：His tag
Tags：FGF-6
Descriptions：Interleukin-34 (IL-34) is a 30 kDa cytokine with 223 amino acid residues. IL-34 is a ligand of CSF-1R and secreted from CSF-1R expressing cells like myeloid cells, epithelial cells, endothelial cells, fibroblasts, and neurons. IL-34 mediates cell survival, proliferation, cytokine/chemokine expression, and migration via activating several signaling pathways. Moreover, it also plays a critical role in developing and maintaining the mononuclear phagocytic system.
Tags：IL-34
Descriptions：Interleukin 34 (IL-34) is a 23.98 kDa cytokine with 216 amino acid residues. IL-34 is a ligand of the colony-stimulating factor 1 receptor (CSF-1R) and is mainly secreted from the adrenal, frontal lobe, and cortex. IL-34 play a vital role in the proliferation, survival, differentiation, and migration of myeloid cells. These functions are mediated by IL-33 activating ERK1 /2, JAK, and PI3K/AKT signal pathways.
Tags：IL-34
Descriptions：C-X-C motif chemokine 3 (CXCL3) also named Growth-regulated oncogene gamma (GROγ), which is a chemokine of the intercrine alpha family. CXCL3 is a 8kDa protein containing 73 amino acid residues. During inflammation, CXCL3 is activated by the TNF and IL-1 which mediates the monocytes migration and adhesion by targeting the CXCR2. CXCL3 activates the JNK activity which induce the cell differentiation.
Applications：His tag
Tags：CXCL3
Descriptions：Interleukin 16(IL-16) predicts a molecular mass of 13.5 kDa, encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication, and signaling process of this cytokine is mediated by CD4.
Tags：IL-16
