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Total 34 Pages/ 331 Results
Choosed: Cytokine Clear All
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    Human IL-15 protein

    Views(94) Publications(0) Catalog No(PRP1063)

    Descriptions:Interleukin-15 (IL-15) is a 14-15 kDa glycoprotein with immune regulatory functions in many diverse cell types. IL-15 can be constitutively expressed in a variety of cell types stored as intracellular protein in the cytoplasm as well as transport to the cell surface, while only secreted from some cell types including monocytes, dendritic cells, epithelial cells, bone marrow stromal cells, and fibroblasts. As a pleiotropic cytokine, IL-15 mediates the crosstalk between innate immunity and adaptive immunity whose principal role is to kill virally infected cells. IL-15 plays a crucial role in the development, differentiation, and survival of NK cells. In monocytes, IL-15 induces the production of IL-8 and monocyte chemotactic protein 1 (MCP-1), which recruits neutrophils and monocytes to sites of infection. IL-15 can also act as a chemo-attractant in T lymphocytes and regulate the differentiation of T lymphocytes.

    Tags:IL-15

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    Human IGF-I Protein, His tag (Animal-Free)

    Views(94) Publications(0) Catalog No(PRP1933)

    Descriptions:Insulin like Growth Factors 1 (IGF-I) is a 7.79 kDa member of the Insulin-like Growth Factors with 71 amino acid residues. IGF-I is mainly expressed from liver, adipose tissue, Endometrial stromal cells, Leydig cells, and can be isolated from plasma. IGF-I mediating the protein anabolic and promoting effect of pituitary growth hormone. IGF-I also affects metabolism of glycogen, DNA synthesis and glucose uptake via binding to IGF-I receptor.

    Tags:IGF-I

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    Human/Mouse BMP-2 Protein

    Views(94) Publications(0) Catalog No(PRP1076)

    Descriptions:Bone morphogenetic protein-2 (BMP-2) is a kind of bone growth regulator, belonging to protein transforming growth factor-β(TGF-β) superfamily. BMP-2 protein is involved in hedgehog pathway, TGF-β signaling pathway and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMP, which have been proved to be effective in inducing osteoblast differentiation in many cell types. The active form of BMP-2 can be composed of dimers of two identical proteins or heterodimers of two related bone morphogenetic proteins.

    Tags:BMP-2

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    Human IL-23 p19 Protein, His tag (Animal-Free)

    Views(93) Publications(0) Catalog No(PRP1909)

    Descriptions:Human IL-23 p19 Protein, His tag (Animal-Free), expressed in E. coli

    Tags:IL-23 p19

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    Human IL-32α Protein, His tag (Animal-Free)

    Views(92) Publications(0) Catalog No(PRP1904)

    Descriptions:Human IL-32α Protein, His tag (Animal-Free), expressed in E. coli

    Tags:IL-32α

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    Human BMP-7 Protein, His tag (Animal-Free)

    Views(92) Publications(0) Catalog No(PRP1199)

    Descriptions:Bone Morphogenetic Protein-7 (BMP-7) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP7 can significantly inhibit TGF-β through binding with TGF-β receptor and trigger SMAD transcription factors, such as SMAD 1 /5/8. It plays a vital role in inhibiting the expansion of kidney damage and promoting the differentiation of osteoblasts.

    Applications:His tag

    Tags:BMP-7

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    Rat IL-6 Protein

    Views(88) Publications(0) Catalog No(PRP1201)

    Descriptions:Interleukin-6(IL-6) is encoded by the IL-6 gene and acts as both a pro-inflammatory and anti-inflammatory cytokine.It is secreted by T cells and macrophages to stimulate immune response.

    Applications:No tag

    Tags:IL-6

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    Mouse VEGF165 Protein, His tag

    Views(86) Publications(0) Catalog No(PRP1172)

    Descriptions:Vascular Endothelial Growth Factors 165 (VEGF165) is a potent growth and angiogenic cytokine which belongs to the VEGF family, includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF165 is an abundant glycosylated cytokine composed of two identical 165 amino acid chains.

    Tags:VEGF165

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    Human IL17F protein,His tag

    Views(86) Publications(0) Catalog No(PRP1944)

    Descriptions:Interleukin-17F(IL-17F) is a cytokine with similar sequence to IL-17.The most significant role of IL-17 is to participate in inducing and mediating pro-inflammatory reaction.

    Applications:His tag

    Tags:IL-17F

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    Vibriocholerae Toxin B Protein

    Views(86) Publications(0) Catalog No(PRP3005)

    Descriptions:Cholera toxin (CT) is an AB5 enterotoxin produced by Vibrio cholerae and is responsible for the disease manifestations. Several publications indicate that the toxin binds to glycoprotein and that the B-chain binds to GM1 ganglioside pentasaccharide on the cell surface.

    Tags:Toxin B

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