| Product name | Mouse FGF-4 Protein |
| Sequence | Amino acid sequence derived from Mouse FGF4 (P11403) (Ser67-Leu202) was expressed. |
| Applications | No tag |
| Applications notes | Mouse |
| Activity | Testing in progress |
| Protein length | The recombinant Mouse FGF4 Protein consists of 136 amino acids and predicts a molecular mass of 15.15 kDa. |
| Preparation method | E.coli |
| Purity | > 95 % as determined by SDS-PAGE |
| Molecular Formula | 15.15 KDa |
| Alternative | HST-1, Transforming protein KS3, HBGF-4 |
| Formulation | Lyophilized from sterile 20mM Tris，50mM NaCl, pH 8.0. |
| Features & Benefits | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 15.15 KDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development. |
| Gene ID | 14175 |
| Alternative | HST-1, Transforming protein KS3, HBGF-4 |
| Accession | P11403 |
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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