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Mouse Adiponectin Protein, His tag

Mouse Adiponectin Protein, His tag

Views(18) Publications(0) Catalog no(PRP1304)
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Specification

Product name Mouse Adiponectin Protein, His tag
Sequence Amino acid sequence derived from Mouse Adiponectin (Q60994) (Val21-Asn247) was expressed.
Applications His-tag
Applications notes Mouse
Activity Testing in progress
Protein length The recombinant Mouse Adiponectin consists of 227 amino acids and predicts a molecular mass of 24.6 kDa.
Preparation method E.coli
Purity > 98 % as determined by SDS-PAGE
Molecular Formula 24.6 KDa
Alternative rMugAcrp30/Adipolean, Adiponectin, ACRP30, APM-1, ADIPOQ, ACDC

Product Properties

Formulation Lyophilized from sterile 20mM Tris,150mM NaCl, pH 8.0.
Features & Benefits < 0.1 EU per μg of the protein as determined by the LAL method.
Molecular weight 24.6 KDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage instructions Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
Gene ID 11450
Alternative rMugAcrp30/Adipolean, Adiponectin, ACRP30, APM-1, ADIPOQ, ACDC
Accession Q60994

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