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Mfn2 Polyclonal Antibody

Mfn2 Polyclonal Antibody

Views(1076) Publications(1) Catalog no(ABP51785)
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Specification

Product name Mfn2 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Mfn2
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative MFN2; CPRP1; KIAA0214; Mitofusin-2; Transmembrane GTPase MFN2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background MFN2 encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. Mitofusin-2 is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Gene ID 9927
Alternative MFN2; CPRP1; KIAA0214; Mitofusin-2; Transmembrane GTPase MFN2
Others Mfn2 Polyclonal Antibody detects endogenous levels of Mfn2 protein.
Accession O95140
Observed Band(KD) 86

Image & description

Fig. Western Blot analysis of various cells using Mfn2 Polyclonal Antibody diluted at 1:1000.

Fig. Western Blot analysis of various cells using Mfn2 Polyclonal Antibody diluted at 1:1000.

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