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Human Sonic Hedgehog Protein

Human Sonic Hedgehog Protein

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Specification

Product name Human Sonic Hedgehog Protein
Sequence Amino acid sequence derived from Human SHH (Q15465.1) (Gly25-Gly197) was expressed.
Activity Testing in progress.
Protein length The recombinant Human SHH consists of 176 amino acids with His tag at N terminus and predicts a molecular mass of 23.48 kDa.
Preparation method E. coli
Purity > 98 % as determined by SDS-PAGE
Alternative HHG1 Protein, Human; HLP3 Protein, Human; HPE3 Protein, Human; MCOPCB5 Protein, Human; SMMCI Protein, Human; Sonic hedgehog Protein, Human; TPT Protein, Human; TPTPS Protein, Human

Product Properties

Formulation Lyophilized from PBS, pH 7.5.
Molecular weight 23.48 kDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human SHH protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Storage instructions Lyophilized recombinant Human SHH protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping The product is shipped at ambient temperature.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important roles in the division of adult stem cells and the development of certain cancers and other diseases.
Gene ID 6469
Alternative HHG1 Protein, Human; HLP3 Protein, Human; HPE3 Protein, Human; MCOPCB5 Protein, Human; SMMCI Protein, Human; Sonic hedgehog Protein, Human; TPT Protein, Human; TPTPS Protein, Human
Accession Q15465

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