| Product name | Human/Mouse/Rat GDF11 Protein, His tag |
| Sequence | Amino acid sequence derived from Human/Murine/Rat GDF-11(Asn299-Ser407)(O95390)was expressed. |
| Applications | His-tag |
| Applications notes | Human/Mouse/Rat |
| Activity | Testing in progress |
| Protein length | The recombinant Human/Mouse/Rat GDF-11 consists of 109 amino acids and predicts a molecular mass of 12.6 kDa. |
| Preparation method | E.coli |
| Purity | > 95 % as determined by SDS-PAGE |
| Molecular Formula | 12.6 KDa |
| Alternative | bone morphogenetic protein 11, Growth/Differentiation Factor-11, GDF-11, BMP11 |
| Formulation | Lyophilized from sterile 20mM Tris，50mM NaCl, pH 9.0. |
| Features & Benefits | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 12.6 KDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Vascular GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves the arrest of the progenitor cell cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggest that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant Human/Murine/Rat GDF-11 is highly homologous to myostatin/GDF-8, sharing 90% amino acid sequence identity |
| Gene ID | 10220 |
| Alternative | bone morphogenetic protein 11, Growth/Differentiation Factor-11, GDF-11, BMP11 |
| Accession | O95390 |
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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