| Product name | Human Haptoglobin Protein, His tag |
| Sequence | Amino acid sequence derived from Human Haptoglobin (AAA88080.1) (Ile162-Asn406) was expressed with 6×His tag at N-terminus. |
| Activity | Testing in progress. |
| Protein length | The recombinant Human Haptoglobin consists of 245 amino acids and predicts a molecular mass of 27.2 kDa. |
| Preparation method | E. coli |
| Purity | > 95 % as determined by SDS-PAGE |
| Alternative | Haptoglobin |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Features & Benefits | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 29.5 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized Haptoglobin protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Haptoglobin is a glycoprotein, which is synthesized in the liver and circulates in the blood. Haptoglobin is usually produced by liver cells, but it is also produced by other tissues, such as skin, lung and kidney. It is a positive acute phase protein, which binds to free hemoglobin and removes it from circulation to prevent kidney injury and iron loss after hemolysis. Decreased levels can be seen in hemolysis and impaired liver function. A high level is a sign of acute or chronic inflammation. Hemoglobin deficiency or hypohaptoglobinemia is caused by mutation of haptoglobin gene and/or its regulatory region. Haptoglobin is also related to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, susceptibility to primary sclerosing cholangitis, idiopathic Parkinson's disease and the reduction of the incidence of plasmodium falciparum malaria. |
| Gene ID | 3240 |
| Alternative | Haptoglobin |
| Accession | P00738 |
Fig.SDS-PAGE analysis of Human Haptoglobin Protein, His tag
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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