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Human Galectin-10 Protein, His tag (Animal-Free)

Human Galectin-10 Protein, His tag (Animal-Free)

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Specification

Product name Human Galectin-10 Protein, His tag (Animal-Free)
Sequence Amino acid sequence derived from human Galectin-10 (Ser 2-Arg 142).
Protein length 37 kDa
Preparation method E. coli
Purity >98% as determined by SDS-PAGE.
Alternative GAL10, Gal-10, LGALS10, LGALS10A, LPPL_HUMAN

Product Properties

Features & Benefits Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.
Molecular weight 37 kDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage instructions Please store the whole kit at 4°C upon receipt ,and protect from light. The kit is valid for 20 months. Please refer to the table below Materials supplied and Storage conditions to store all the components.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Galectin-10 (Gal-10) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. It has been reported that galectin-10 is presented in eosinophils but also detected in basophils and macrophages. Accumulated evidence indicates that galectin-10 spontaneously forms Charcot-Leyden crystals (CLCs), participating in allergic responses and related inflammatory reactions. Several binding partners for galectin-10 have been identified, including eosinophil granule cationic ribonucleases, eosinophil-derived neurotoxin (EDN, RNS2), and eosinophil cationic protein (ECP, RNS3), demonstrating the interaction is essential for eosinophil differentiation and granulogenesis.
Alternative GAL10, Gal-10, LGALS10, LGALS10A, LPPL_HUMAN
Accession Q05315

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