| Product name | Human BMP-7 Protein |
| Sequence | Amino acid sequence derived from Human BMP7(Met315-His431) (P18075)was expressed. |
| Applications | No tag |
| Applications notes | Human |
| Activity | Testing in progress |
| Protein length | The recombinant BMP7 consists of 117 amino acids and predicts a molecular mass of 13.2 kDa. |
| Preparation method | E.coli |
| Purity | > 98 % as determined by SDS-PAGE |
| Molecular Formula | 13.2 KDa |
| Alternative | bone morphogenetic protein 7,Osteogenic Protein-1(OP-1),BMP7 |
| Formulation | Lyophilized from sterile 20mM Tris-HCl，250mM NaCl, pH 8.0. |
| Features & Benefits | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 13.2 KDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Bone morphogenetic protein 7 (BMP-7) is a multifunctional ligand protein belongs to the TGF-β family. BMP-7 is involved in regulating the proliferation, invasion, and migration of cancer cells, and is associated with various human tumors. BMP-7 binds to ALK2 or ACVR2A/BMPR2 excitation signals, which are regulated and terminated by SMADs. BMP-7 is involved in the BMP-7 Smad1/5/9 signaling pathway and is associated with the epithelial mesenchymal transition (EMT) process. BMP-7 also eliminates vascular inflammation, maintains vascular integrity, weakens vascular calcification, and stimulates in situ phosphorylation deposition. The growth factor domain of human BMP-7 shares 98% aa sequence identity with mouse and rat BMP-7. |
| Gene ID | 655 |
| Alternative | bone morphogenetic protein 7,Osteogenic Protein-1(OP-1),BMP7 |
| Accession | P18075 |
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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