| Product name | Human BMP-15 Protein, His tag |
| Sequence | Amino acid sequence derived from Human BMP15 (Gln268-Arg392) (O95972) was expressed. |
| Applications | His tag |
| Applications notes | Human |
| Activity | Testing in progress |
| Protein length | The recombinant Human BMP15 Protein consists of 125 amino acids and predicts a molecular mass of 14.07 kDa. After fusion TrxA, it predicts a molecular mass of 34.1 kDa. |
| Preparation method | E.coli |
| Purity | >98 % as determined by SDS-PAGE |
| Molecular Formula | 14.2 KD |
| Alternative | bone morphogenetic protein 15, Growth/Differentiation Factor-9B, GDF-9B, ODG2, POF4, BMP15 |
| Formulation | Lyophilized from sterile 20 mM Tris, 50 mM NaCl, pH8.0. |
| Features & Benefits | <0.1 EU per μg of the protein by the LAL method. |
| Molecular weight | 14.2 KD |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Bone morphogenetic protein 15 (BMP-15), also known as GDF-9B, is a TGF-β superfamily ligand that is expressed by oocytes throughout folliculogenesis, and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis. It also induces GC production of stem cell factor which, in turn, negatively regulates BMP-15 expression in oocytes. BMP-15 blocks the FS-induced GC expression of FSH R and multiple steroidogenic molecules. |
| Gene ID | 9210 |
| Alternative | bone morphogenetic protein 15, Growth/Differentiation Factor-9B, GDF-9B, ODG2, POF4, BMP15 |
| Accession | O95972 |
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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